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Stars symbolize the evaluation position, or the extent of critique supporting the submitted (SCV) document. This value is calculated by NCBI dependant on knowledge in the submitter.
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ClinVar has an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice web page are a comparatively common cause of aberrant splicing (PMID: 17576681, 9536098). Algorithms created to predict the effect of sequence modifications on RNA splicing recommend that this variant might produce or reinforce a splice web site. In summary, the obtainable proof is at this time inadequate to find out the part of this variant in disease. Therefore, it's been labeled like a Variant of Uncertain Importance. Okay
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Stars depict the mixture overview standing, or the level of evaluation supporting the aggregate germline classification for this VCV record.
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